报 告 人：顾勇 研究员

　　报告时间：2016年10月26日（星期三）上午10:00-12:00 

　　报告地点：C1影像楼209会议室

　　报告人简历：

　　顾勇博士，1993-1997年就读于厦门大学生物系，获理学学士学位。1997-2002年就读于中国科学院生物物理研究所，获理学博士学位。2002-2011年，在美国圣路易斯华盛顿大学医学院从事博士后研究工作，2010年起任Senior Scientist。2011年11月起任中国科学院上海生命科学研究院神经科学研究所研究员，研究组组长。顾勇博士的研究兴趣主要在于空间运动感知的机制，以及多种感知觉整合的神经基础。

　　报告摘要：

　　To form a unified percept, the brain needs to integrate information from different sensory modalities. Although several brain areas have been found to encode multisensory information, little is known about how it is decoded and accumulated in downstream decision-making areas. We recorded from single neurons in lateral intraparietal area (LIP) in macaque monkeys performing a visual-vestibular multisensory decision-making task. We found that: (i) the rising phase of the vestibular ramping activity was substantially earlier than the visual one, indicating that LIP accumulates vestibular acceleration signals but visual velocity signals; (ii) LIP ramping activity in the visual, but not vestibular condition, significantly depended on the task-difficulty, a hallmark of gradual evidence accumulation in decision-making; (iii) task parameters (choice and modality) were randomly mixed at the single neuron level but largely separated at the population level in LIP; and (iv) when presented simultaneously, the two distinct sources of evidence (visual and vestibular) were integrated, resulting in an enhanced divergence of LIP population trajectories. However, the improvement is far from that predicted from optimal cue integration theory, as observed in the behavior. Our results may place important constraints on theoretical considerations for neural basis of multisensory integration and multisensory decision-making.